Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Juventus' faint Serie A title hopes were further dented by local rivals Torino, who fought their way back to earn a deserved 1-1 draw in Friday night's Turin derby.
The Copa del Rey derby match between Real Betis and Sevilla was suspended after a pole hurled from the stands hit Sevilla player Joan Jordan in the head on Saturday.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.
Olivier Giroud's early strike earned AC Milan a narrow 1-0 win over Torino on Tuesday to send Stefano Pioli's side top of the Serie A standings.
Torino defender Lyanco will undergo a medical on Monday as he closes on a move to the Premier League with Southampton, according to Sky in Italy.