Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Juventus' faint Serie A title hopes were further dented by local rivals Torino, who fought their way back to earn a deserved 1-1 draw in Friday night's Turin derby.
The Copa del Rey derby match between Real Betis and Sevilla was suspended after a pole hurled from the stands hit Sevilla player Joan Jordan in the head on Saturday.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.
Olivier Giroud's early strike earned AC Milan a narrow 1-0 win over Torino on Tuesday to send Stefano Pioli's side top of the Serie A standings.
Torino defender Lyanco will undergo a medical on Monday as he closes on a move to the Premier League with Southampton, according to Sky in Italy.
Watford are in talks to sign Torino defender Lyanco as they aim to further strengthen their squad on their return to the Premier League.
Lazio revived their hopes of Champions League qualification and subjected AC Milan to a second consecutive Serie A defeat as Joaquin Correa scored twice in a 3-0 win.
Benevento dented Juventus's Serie A title hopes on Sunday when Adolfo Gaich's second-half strike sealed a shock 1-0 victory in Turin.
Lautaro Martinez's late winner stretched Inter's winning run to eight games, while Cristiano Ronaldo answered his critics with a perfect hat-trick.
Real Madrid forward Karim Benzema struck an 88th-minute equaliser to snatch a 1-1 draw at La Liga leaders Atletico Madrid and keep his side in the title race.
Lazio's Serie A match against Torino descended into farce on Tuesday as they turned up at the Stadio Olimpico despite Torino being in quarantine more than 600km away.
Serie A leaders Milan were stunned 2-0 by Spezia to give Inter the chance to leapfrog them, while Atletico Madrid went eight points clear in La Liga.
Real Madrid drew level with Atletico Madrid at the top of La Liga with a 2-0 win over Granada, plus all the latest from Serie A and La Liga.
Real Madrid ended Atletico Madrid's 26-game unbeaten run with a 2-0 win at the Alfredo Di Stefano Stadium to move within three points of the La Liga leaders.
Barcelona's dismal start to the La Liga season continued as a second-half winner from substitute Alvaro Negredo handed Cadiz another major top-flight scalp.
Sergio Ramos' late penalty helped secure Real Madrid a 3-2 victory at Real Betis, who finished the La Liga match with 10 men, plus all the latest from around Europe.
Arsenal midfielder Lucas Torreira is no longer a priority signing for Torino, club director Davide Vagnati told Sky in Italy.
Arsenal are in talks with Serie A side Torino over a loan deal for midfielder Lucas Torreira with a view to a permanent move.
Fulham have confirmed the signing of Ola Aina on a season-long loan from Torino.