Thursday 27 October 2016 14:18, UK
There are recalls for Ben Morgan, Tom Wood and Jonny May in Eddie Jones' latest squad, but what about the players looking to make their first appearance for England?
Alex Lozowski
Initially brought in by Saracens to learn under the tutelage of Owen Farrell, Lozowski was thrown into the mix early after Farrell picked up a back injury at the beginning of the season.
The 23-year-old's first start for his new club was in the Premiership opener against Worcester at Twickenham, and he made the perfect start with a try, along with 15 points from the boot.
Jones saw enough potential from Lozowski to draft him into his initial training camp ahead of Danny Cipriani last month, and the Wasps man has once again been overlooked in Jones' final squad in favour of Lozowski.
With the likes of Farrell and George Ford the front runners to feature at fly-half for England - and Alex Goode and Henry Slade able to cover the position in case of injury - it's unclear how much game time Lozowski will get in November, but it speaks volumes that the coach has backed the young playmaker in his breakthrough season for the European and Premiership champions.
Ben Te'o
The latest of England's cross-code internationals, Worcester centre Te'o toured Australia with England in the summer but is yet to make an appearance for Jones' side.
Born in Auckland to an English mother, Te'o announced in December that he was to turn down an offer from Leinster as well as a rumoured return to Rugby League in favour of a move to Worcester, in a deal reportedly designed to further his England ambitions.
No stranger to the international stage, the 28-year-old represented Samoa in the 2008 Rugby League World Cup, scoring twice in his sole appearance against France.
Te'o became one of Leinster's star players in 2015/16, helping them reach the Guinness PRO12 final, earning himself the club's Player of the Year award in the process.
Since his move to Worcester in the summer, Te'o has made four appearances for the Warriors and scored two tries.
Nathan Hughes
Fijian-born Hughes has been in superb form for Wasps for some time, but only qualified for England in the summer.
This season he has the most carries for Wasps in the Premiership, the second-most metres made behind Christian Wade, and only beaten by Jimmy Gopperth for the highest tackle count.
Hughes has been drafted into the England squad at the first time of asking following his qualification, but which position he will play is as yet undetermined. The 25-year-old can cover lock in a pinch, but it's most likely he will feature on the side of the scrum.
Billy Vunipola is still England's first-choice No 8, and with Ben Morgan recalled to cover the back of the scrum, it is apparent that Jones sees Hughes as a flanker.
Kyle Sinckler
Twice a tourist with England, Harlequins prop Sinckler is yet to win his first cap for his country.
The 23-year-old featured for England's non-cap international against the Barbarians in May 2014 before touring New Zealand that summer, and more recently found himself as an unused member of the squad that secured a 3-0 series whitewash in Australia.
Having represented England at U16, U18, U19 and U20 levels, Sinckler has gone on to watch former junior level team-mates Ford, Anthony Watson, Jack Nowell and Billy Vunipola earn senior honours, and will be keen to follow in their footsteps before too soon.
A force up front for Harlequins, Sinckler has made 87 appearances for the club and is touted by many as Dan Cole's successor in the England tighthead role.
Mike Haley
Since making his Sale debut in the 2013 LV= Cup semi-final, Sale academy product Haley has established himself as his club's first choice full-back, going on to make 57 appearances for the Sharks and scoring 10 tries.
Before making his mark on senior rugby, Haley represented England U18, and also spent two months playing in the U19 Currie Cup in South Africa.
His recent form for Steve Diamond's side led to selection for the England Saxons in their tour of South Africa earlier this year, showcasing his trademark runs on his run-out in Bloemfontein.
Haley picked up a shoulder injury during the tour, so has only featured for Sale once this season, a 33-minute appearance against Bath in which he managed 10 carries.
Charlie Ewels
Bournemouth-born Ewels was a key member of the England U20 team that won the 2014 Junior World Championship in New Zealand, partnering Maro Itoje in the second row.
The 21-year-old made his senior debut for Bath against Glasgow in the Champions Cup in the same year, and went on to make eight first-team appearances whilst still in the academy.
In six games for Bath in the Premiership this season Ewels has put in 62 tackles, the most of anyone from Todd Blackadder's side, and 11th overall in the competition.
A hard-hitting second rower, Ewels will push the likes of Joe Launchbury, Courtney Lawes and Atwood for a place in the team when Jones names his first matchday 23.
