A round-up of Saturday's Investec Champions Cup action, where Northampton and Saracens made winning starts but Exeter were beaten by Sharks in South Africa.
Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Henry Slade proved his fitness ahead of England's Autumn Nations Series opener but could not prevent Exeter from suffering defeat by Harlequins.
Northampton bounced back from their derby disappointment in style as they trounced Sale while Newcastle earned their first Premiership victory in over a year.
Leicester made it three wins from four under Michael Cheika as they beat rivals and defending champions Northampton 24-8 on Saturday.
England back row Ben Earl scored two tries as Saracens made it three wins from three in the Premiership this season with a 29-14 victory over Exeter.
Wales lock Dafydd Jenkins looks increasingly unlikely to be fit for the autumn internationals.
Leigh Halfpenny celebrated a first Gallagher Premiership try as Harlequins picked up a 28-14 bonus-point victory over Newcastle at Twickenham Stoop.
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