Bayern Munich cruised past Bayer Leverkusen 4-0 to end a four-game winless run in the Bundesliga and climb into second place.
Barcelona slumped to a 1-0 home defeat by Rayo Vallecano which pushed leaders Real Madrid a step closer to the La Liga title.
Karim Benzema's last-gasp winner sealed Real Madrid's stunning comeback as they recovered from 2-0 down to beat Sevilla 3-2.
Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Real Madrid were crowned Spanish Super Cup champions after goals from Luka Modric and Karim Benzema earned them a 2-0 win over Athletic Bilbao.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.
Serie A leaders Napoli lost for the first time this season as Inter Milan reinvigorated their own title bid with a 3-2 win at the San Siro.
Zlatan Ibrahimovic and Franck Kessie gave AC Milan a 2-1 win at 10-man Roma to inflict Jose Mourinho's first-ever home Serie A defeat and stay level with leaders Napoli.
Kylian Mbappe ended a four-game scoreless streak for PSG with a late penalty that helped the capital side extend their Ligue 1 lead to nine points.
Gareth Bale scores for Real Madrid in their 3-3 draw with Levante, while Tammy Abraham registered two assists in a win for Jose Mourinho's Roma.
Lille have been crowned Ligue 1 champions after a 2-0 victory at Angers on the final day of the season
Timothy Weah and Jonathan David both scored as Lille won 3-0 at Bordeaux on Wednesday to stay top of the French league ahead of Lyon and PSG.
Real Madrid drew level with Atletico Madrid at the top of La Liga with a 2-0 win over Granada, plus all the latest from Serie A and La Liga.
AC Milan restored their five-point lead at the top of Serie A with a 2-1 win at Sampdoria on Sunday.
Lionel Messi's late penalty edged Barcelona to a 1-0 victory at home to Real Sociedad to ease the pressure on manager Quique Setien.
Barcelona were made to work for their win against third-place Getafe in La Liga on Saturday while PSG were held 4-4 by Amiens in France.
Mauro Icardi rediscovered his scoring touch to help PSG beat Nantes 2-1 in Ligue 1 while Borussia Dortmund and RB Leipzig were knocked out of the DFB-Pokal in Germany.
Karim Benzema scored for the first time in a Madrid derby at the Bernabeu as Real Madrid beat Atletico Madrid 1-0.
Quique Setien suffered his first defeat as Barcelona boss as Valencia secured a 2-0 win to preserve their unbeaten La Liga home record this season.
Real Madrid moved top of La Liga, until Sunday evening at least, with a 2-1 win at Alaves while Bayern Munich were beaten by Bayer Leverkusen.