A costly mistake from goalkeeper Thibaut Courtois helped Alaves secure a 2-1 La Liga victory over Real Madrid at the Alfredo Di Stefano stadium.
Zlatan Ibrahimovic made a winning return to the AC Milan team as his quickfire double won the Milan derby, while Real Madrid and Barcelona suffered shock defeats.
Sergio Ramos' late penalty helped secure Real Madrid a 3-2 victory at Real Betis, who finished the La Liga match with 10 men, plus all the latest from around Europe.
Robert Lewandowski scored another double to send Bayern Munich through to the DFB-Pokal quarter-finals as Lazio missed the chance to go second in Serie A.
Liverpool defender Nathaniel Phillips has been loaned back to Stuttgart until the end of the season, just 17 days after being recalled.
Stuttgart have appointed Holstein Kiel's Tim Walter as their new head coach from next season.
Bayern Munich moved closer to clinching another Bundesliga title with a hard-fought 1-0 win over 10-man Werder Bremen.
Jadon Sancho scored twice as Borussia Dortmund moved to the top of the Bundesliga with a 2-1 victory over Mainz.
Suat Serdar hit the only goal of the game as Schalke eased their Bundesliga relegation fears with victory at bottom club Hannover.
Marco Reus' stoppage-time strike settled a five-goal thriller against 10-man Hertha Berlin to lift Borussia Dortmund three points clear at the top of the Bundesliga.
Bayern Munich seized the Bundesliga lead from Borussia Dortmund by demolishing Wolfsburg 6-0 on Saturday.
Werder Bremen maintained their unbeaten record in 2019 but were held to a 1-1 draw at home to struggling Stuttgart.
Stuttgart's poor run of form continued as they lost 3-1 to RB Leipzig, who consolidated fourth place in the Bundesliga.
Werder Bremen celebrated their 120th anniversary in style, scoring three first-half goals on their way to a comfortable 4-0 Bundesliga victory over Augsburg.
Augsburg striker Alfred Finnbogason scored a hat-trick and had a fourth ruled out for offside as he led his team to a crucial 3-0 win over Mainz on Sunday.
Bayern Munich moved back up to second in the Bundesliga and cut Borussia Dortmund's lead to six points with a 4-1 home win over Stuttgart.
Borussia Dortmund restored their six-point lead at the top of the Bundesliga with a 1-0 victory at RB Leipzig.
Bayern Munich thrashed Borussia Dortmund 5-0 to take over top spot in the Bundesliga on a landmark night for Robert Lewandowski.
Fulham's highly-rated 18-year old midfielder Matt O'Riley could soon become the latest young England talent to head for the Bundesliga.
Bayern Munich have agreed a deal to sign French World Cup winner Benjamin Pavard from Stuttgart this summer.