Henry Slade held his nerve as Exeter launched their Champions Cup campaign with a stunning 19-18 victory over Toulon.
Former Chelsea and Brighton manager Graham Potter has declined the opportunity to take charge at Lyon.
La Rochelle broke Ulster hearts in the very final play to book a last-16 spot, while Ospreys, Saracens, Sharks and Bulls won too.
Leicester Tigers claimed a second Champions Cup win from as many rounds, beating Clermont, while Saracens dug deep to win at Lyon.
Lyon won their first major honour for 89 years as they claimed a thoroughly deserved 30-12 Challenge Cup final victory over Toulon.
Wasps bowed out of the European Challenge Cup at the semi-final stage as they were beaten 20-18 by a powerful Lyon side at the Matmut Stadium.
Karim Benzema's last-gasp winner sealed Real Madrid's stunning comeback as they recovered from 2-0 down to beat Sevilla 3-2.
Newcastle are extremely close to completing a £40m move for Bruno Guimaraes.
A round-up of Friday evening's three Challenge Cup matches, which saw Gloucester, Lyon and Toulon seal victories.
A round-up of all the action from Friday's opening two matches of this season's European Challenge Cup.
France's Fabien Galthie has named nine uncapped players in his 42-man squad for next month's Tests vs Argentina, Georgia and New Zealand.
Exeter will face Leinster in the quarter-finals of the Heineken Cup after beating Lyon 47-25 at Sandy Park on Saturday.
We look ahead to Saturday's Champions Cup round-of-16 ties, as Wasps welcome Clermont, Munster host Toulouse and Exeter play Lyon.
Wasps are the only English club to be guaranteed home advantage for the Champions Cup round of 16 in a revised format for the knockout phase.
After a genuine renaissance year in 2020, can France go one better and clinch the silverware that alluded them last year in 2021?
We take a look at where European rugby can go next, after the Champions Cup's temporary suspension was confirmed on Monday.
Exeter and Glasgow Warriors' Champions Cup fixtures have been cancelled after a number of Chiefs players and staff tested positive for Covid-19.
Chelsea boss Emma Hayes has paid tribute to the "wonderful" Gerard Houllier and praised the Frenchman for his contributions to women's football.
We pick the standout players from the weekend's Champions Cup action, as Top 14 clubs dominate, alongside English, Irish and Welsh representation.
Gloucester conceded the most points in their Champions Cup history as they started the new campaign with a 55-10 hammering at the hands of Lyon.