Gloucester beat an out-of-sorts Harlequins at Kingsholm as the visitors were blanked in a league game for the first time in a decade.
A round-up of Friday's action, as Bath suffered a setback in their Champions Cup opener and Gloucester came through a tough European Challenge Cup test against Edinburgh
Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Six-try Bath powered their way to a bonus-point victory over Sale Sharks to round off the first block of Gallagher Premiership matches in style.
Handre Pollard scored 14 points as Leicester overturned a 19-8 half-time deficit to claim a 29-26 win against Gloucester in a thrilling Gallagher Premiership encounter.
Leicester made it three wins from four under Michael Cheika as they beat rivals and defending champions Northampton 24-8 on Saturday.
England wing Tom Roebuck scored two tries as Sale secured a breathless 31-27 bonus-point win over Gloucester in the Gallagher Premiership.
Christian Wade scored a hat-trick of tries as Gloucester claimed a remarkable 44-41 Premiership victory over Bristol.
Michael Cheika's reign as Leicester head coach began in dramatic winning fashion as the Tigers claimed a 17-14 Gallagher Premiership victory at Sandy Park.
Gloucester-Hartpury staged a sensational comeback to retain their Allianz Premiership Women’s Rugby title with a 36-24 victory over Bristol Bears.
Gloucester's aim of finishing a mixed season with a second piece of silverware was ended with a 36-22 defeat by the Sharks in the Challenge Cup final.
All of the action from the final day of the Gallagher Premiership regular season, which saw the Play-Offs decided.
Championship clubs have welcomed the approval of promotion to the Gallagher Premiership as a "new era" for the professional game in England.
Northampton broke numerous records as they battered Gloucester 90-0 in the Gallagher Premiership.
Gloucester are into the Challenge Cup final for a fifth time after beating Italian team Benetton 40-23 at Kingsholm.
Exeter and Sale kept alive their Gallagher Premiership play-off hopes with victories over Gloucester and Newcastle Falcons on Sunday.
Northampton marched to a 40-17 Premiership bonus-point win over 14-man Leicester as they reinforced their status as table toppers on derby day.
Santiago Carreras kicked six penalties to steer Gloucester to the European Challenge Cup semi-finals after a 23-13 win over Ospreys at Kingsholm.
Marcus Smith provided the magic as Harlequins edged into the Investec Champions Cup quarter-finals.
The RFU has apologised for an officiating error after Harlequins held off a storming Bath comeback for a win that lifted them back into the Premiership play-off places.