Robert Lewandowski scored another double to send Bayern Munich through to the DFB-Pokal quarter-finals as Lazio missed the chance to go second in Serie A.
Karim Benzema scored for the first time in a Madrid derby at the Bernabeu as Real Madrid beat Atletico Madrid 1-0.
Real Madrid moved top of La Liga, until Sunday evening at least, with a 2-1 win at Alaves while Bayern Munich were beaten by Bayer Leverkusen.
Bayern Munich hammered Borussia Dortmund 4-0 at the Allianz Arena, while Real Madrid also hit four against Eibar to keep up with the pace at the top of La Liga.
Real Sociedad went level on points with La Liga leaders Barcelona after snatching a 2-1 victory against Granada thanks to a late strike from Cristian Portu.
Romelu Lukaku's goal was not enough for Inter Milan as they missed out on the chance to steal top spot in Serie A from Juventus.
Marseille moved back up to fourth place in Ligue 1 with a 2-1 victory against mid-table Nimes at Stade Velodrome.
Eric Maxim Choupo-Moting was guilty of an extraordinary miss as PSG missed the chance to secure the Ligue 1 title after a 2-2 draw with Strasbourg.
Angel Di Maria set up the opener before scoring a second-half double as PSG extended their Ligue 1 lead with a 3-1 win over Marseille.
Lyon missed the opportunity to move within two points of second-placed Lille by blowing a two-goal lead to draw 2-2 at Strasbourg.
Gelson Martins and Rony Lopes on the scoresheet as Monaco edged further away from trouble with win against Lyon.
PSG extended their advantage at the top of Ligue 1 to 12 points after recording a narrow 1-0 victory over St Etienne.
Remi Walter's 69th-minute penalty gave Nice a third straight home win as Lyon lost 1-0 to end a five-game winning streak in all competitions.
Cesc Fabregas struck the winner for struggling Monaco in a much-needed 2-1 win against Toulouse in Ligue 1 on Saturday.
Monaco's troubles continued as they lost 2-0 at Ligue 1 relegation rivals Dijon in their first match since Thierry Henry's departure.
Edinson Cavani and Kylian Mbappe scored hat-tricks as Ligue 1 leaders Paris Saint-Germain crushed bottom club Guingamp 9-0 on Saturday.
Lille consolidated second spot in Ligue 1 by bouncing back from last weekend's surprise defeat to Toulouse with a 3-1 win at Caen.
Strasbourg players wore special shirts to honour the victims of Tuesday's shooting in the city as they were defeated 2-1 in Reims in Ligue 1.
Nicolas Pepe scored an injury-time penalty to salvage a point for second-placed Lille in a 1-1 draw at home to Reims.
Edinson Cavani's second-half penalty salvaged a point for Ligue 1 leaders Paris Saint-Germain in a 1-1 draw at Strasbourg.
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