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Ruben Amorim claimed the anxiety around Old Trafford affected his players' mentality and admitted he faces a "big challenge" following Sunday's 3-0 defeat to Bournemouth.
Liverpool moved four points clear at the Premier League summit heading into Christmas after Luis Diaz and Mohamed Salah scored twice in a 6-3 win at Tottenham.
Chelsea missed the chance to move to the top of the Premier League table as they were held to a goalless draw with Everton at Goodison Park.
Vitor Pereira made the dream start to life as Wolves head coach as his new side ended a run of four straight defeats with a 3-0 win against Leicester on Sunday.
Brilliant Bournemouth won 3-0 at Old Trafford for the second season running as Manchester United's fortunes continue to yield mixed results under Ruben Amorim.
Gary Neville has called for a "cultural overhaul" at Manchester United following the 3-0 defeat to Bournemouth at Old Trafford.
Jamie Carragher believes Liverpool's 6-3 win against Tottenham was a "performance of champions".
The Sky Sports football writers analyse Sunday's Premier League action as Man Utd discover how harsh the Premier League is if you cannot even do the basics...
Mikel Arteta admits he is "really worried" about Bukayo Saka's hamstring injury that forced him off in the first half against Crystal Palace.
The top stories and transfer rumours from Monday's newspapers...
Fulham missed out on the chance to move into the Premier League's top six after being held to a draw by Southampton, who were being watched by new manager Ivan Juric.
A defiant Ange Postecoglou once again defended Tottenham's approach and said it would not change despite shipping six goals at home to Liverpool.
The latest news and gossip from Man Utd this week...
Follow live updates and in-game clips as Spurs host Liverpool in the Premier League, live on Sky Sports; kick-off 4.30pm. Watch free highlights shortly after full-time.
The Sky Sports football writers analyse Saturday's Premier League action as Morgan Rogers scored against his former club when Aston Villa beat Manchester City.
Aston Villa condemned Manchester City to a sixth defeat in eight Premier League games with a 2-1 win over the reigning champions at Villa Park.
Jamie Carragher says it's "crunch time" for Arsenal and Mikel Arteta as they need to start winning big trophies following their 5-1 win over Crystal Palace.
Arsenal moved three points behind Premier League leaders Liverpool as Gabriel Jesus inspired them to a 5-1 thrashing of Crystal Palace at Selhurst Park.
Alexander Isak scored his first Premier League hat-trick as Newcastle wrapped up a perfect week by thrashing Ipswich 4-0 at Portman Road to move into seventh.