Paris St Germain must wait to secure the Ligue 1 title after a humbling 5-1 defeat to second-placed Lille on Sunday.
Eric Maxim Choupo-Moting was guilty of an extraordinary miss as PSG missed the chance to secure the Ligue 1 title after a 2-2 draw with Strasbourg.
Angel Di Maria set up the opener before scoring a second-half double as PSG extended their Ligue 1 lead with a 3-1 win over Marseille.
Mario Balotelli scored against his former club as Marseille extended their unbeaten run in Ligue 1 to six games with a 1-0 victory over Nice at Stade Velodrome.
Daniel Congre scored a second-half winner as Montpellier ended a five-match winless league run by beating Bordeaux 2-1.
Paris Saint-Germain moved 15 points clear at the top of Ligue 1 after they thrashed Montpellier 5-1 on Wednesday.
PSG extended their advantage at the top of Ligue 1 to 12 points after recording a narrow 1-0 victory over St Etienne.
Remi Walter's 69th-minute penalty gave Nice a third straight home win as Lyon lost 1-0 to end a five-game winning streak in all competitions.
Leaders Paris Saint-Germain suffered their first Ligue 1 defeat of the season as Lyon claimed a deserved 2-1 victory on Sunday evening.
Edinson Cavani struck twice as Paris Saint-Germain continued their march towards the Ligue 1 title with a 4-1 home thrashing of Stade Rennais.
Substitute Moussa Dembele fired a last-gasp winner as Lyon came from behind to defeat St Etienne 2-1 in the Derby Rhone-Alpes.
Montpellier missed the chance to move up to third place in Ligue 1 after being held to a 1-1 draw at relegation-threatened Dijon on Sunday.
Kylian Mbappe grabbed the winner as Paris Saint-Germain beat Nantes 1-0 while Thierry Henry's Monaco suffered defeat by rock-bottom Guingamp.
Amiens climbed out of the Ligue 1 relegation places after a 2-1 win at bottom club Guingamp.
Florian Thauvin fired a hat-trick as Marseille won 3-1 at Amiens to climb to within two points of second-placed Lyon in Ligue 1.
Memphis Depay starred with two goals and two assists as fourth-placed Lyon won at bottom side Guingamp 4-2 in Ligue 1 on Saturday.
Patrick Vieira's Nice slumped to a fourth defeat in five home league games after losing 1-0 against Marseille on Sunday.
Jonathan Bamba fired another double as Lille beat St Etienne 3-1 to narrow the gap on Ligue 1 leaders PSG to five points.
Lille hit back from their midweek defeat in Bordeaux to reclaim second place in Ligue 1 with an emphatic 3-0 home win over Marseille.
PSG maintained their perfect start to the Ligue 1 season as they came from behind to beat Reims 4-1 at the Parc des Princes.