Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Maxi Gomez and Iago Aspas both scored two goals apiece as Celta Vigo finished the season with a 4-2 home victory against in-form Levante.
Champions League quarter-finalists Sevilla will not be playing in Europe next season following a 2-2 draw against Real Betis.
All the latest transfer news and rumours from the European press with Sevilla defender Clement Lenglet reportedly set to sign for Barcelona.
Barcelona's Lionel Messi has won the Sky Sports La Liga Power Rankings by an unprecedented margin - but who else made the top 50?
Atletico Madrid slumped to their first home defeat of the La Liga season as they were beaten 2-0 by Espanyol at the Wanda Metropolitano Stadium.
Barcelona midfielder Philippe Coutinho has topped the penultimate Sky Sports La Liga Power Rankings - but who else made the top 50?
Espanyol secured their La Liga status on Saturday despite being held to a 1-1 home draw by relegated Las Palmas.
Lionel Messi has topped the Sky Sports Power Rankings for a 17th week this season - but who else made the top 50?
Saul Niguez was denied by the crossbar as second-placed Atletico Madrid were held to a 0-0 La Liga draw by Real Betis on Sunday.
Lionel Messi has topped the La Liga Power Rankings - but who else made the top 50 this week?
Sevilla fought back from two goals down to draw 2-2 with Villarreal in La Liga on Saturday.
Athletic Bilbao midfielder Raul Garcia has topped the La Liga Power Rankings - but who else made the top 50?
Levante put breathing space between themselves and the relegation zone after a last-gasp 2-1 win over Las Palmas.
Barcelona's Philippe Coutinho is among the top performers in the La Liga Power Rankings - but who else made the top 50?
Real Madrid brushed aside Las Palmas as two goals from Gareth Bale eased them to a 3-0 win ahead of Tuesday's Champions League quarter-final.
Lionel Messi has achieved unprecedented numbers in the La Liga Power Rankings this week - but who else made the top 50?
Cristiano Ronaldo and Gareth Bale are flying high in the La Liga Power Rankings ahead of the Madrid derby - but who else made the top 50 this week?
Zinedine Zidane says Real Madrid are focused on Saturday's La Liga clash at Las Palmas, despite an upcoming Champions League quarter-final.
Manchester City are closing in on the Premier League title, but who else is set for glory - and misery - around Europe?
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