Peru have clinched the South American play-off spot in their bid to qualify for Qatar 2022, while Brazil broke Argentina's points record in their victory over Bolivia.
Raphina and Philippe Coutinho inspire Brazil to Paraguay win, Argentina dent Colombia's hopes; plus: Rodrigo Bentancur and Alexis Sanchez on target.
Brazil moved within one win of qualifying for next year's World Cup by thrashing Uruguay 4-1 in Manaus, with Leeds' Raphinha scoring twice.
Lionel Messi broke Pele's record for most international goals by a South American footballer with a hat-trick in Argentina's 3-0 win over Bolivia.
Lionel Messi became Argentina's most capped international and scored twice as they beat Bolivia 4-1 to set up a Copa America quarter-final against Ecuador.
Uruguay and Paraguay secured their spots in the Copa America knockout stage as both won 2-0 in Group A, knocking Bolivia out of the tournament.
Lionel Messi scored a stunning free kick as Argentina were held to a 1-1 draw by Chile in their Copa America opener in Rio de Janeiro.
A double by Darwin Machis and Josef Martinez's goal helped Venezuela beat Bolivia 3-1 and advance to the Copa America quarter-finals.
Brazil overwhelmed Peru with three goals in a superb first half to set up a crushing 5-0 victory on Saturday and cruise into the Copa America quarter-finals.
Striker Paolo Guerrero led Peru to a key 3-1 win over Bolivia on Tuesday that improved the team's chances of advancing to the knockout stage of Copa America.
With Neymar watching from afar, it was Philippe Coutinho who came through for Brazil in the Copa America opener.
Neymar has criticised conditions at Bolivia's Estadio Hernando Siles in La Paz, describing it as "inhuman" to play at such severe altitude.
Brazil were held to a 0-0 draw away to Bolivia in a World Cup Qualifier on Thursday with home goalkeeper Carlos Lampe in outstanding form.
The Copa America returns this summer, but when and where is it, who could feature from the Premier League and how are the teams shaping up ahead of the tournament?
Chile's World Cup qualification hopes were left on a knife edge after crashing to a 1-0 defeat against Bolivia.
From Argentina to Australia, read our World Cup qualifying update ahead of this week's internationals...
An Argentina side reeling from the shock suspension of Lionel Messi crashed to a 2-0 defeat against Bolivia on Tuesday.
From Argentina to Australia, read our World Cup qualifying update ahead of this week's internationals...
Bolivia have been docked four World Cup qualifying points for fielding an ineligible player - Nelson Cabrera - in two matches.
Uruguay were denied an impressive win in Colombia as Yerry Mina's 84th-minute strike earned a 2-2 draw.