Alex Goode produced a virtuoso display to celebrate his entry into Saracens' history books, while Theo McFarland stood out in win vs Sale.
Owen Farrell and Jonny May have withdrawn injured from England's training camp squad ahead of the Autumn Nations Series.
Marcus Smith proved the difference for Harlequins as they put an end to Sale's unbeaten start in the Premiership this season.
Five-try Sale Sharks eased to a 37-14 Gallagher Premiership victory over London Irish at the AJ Bell Stadium on Friday.
Premiership Rugby wants to introduce an independent regulator to oversee clubs' finances.
Recap Saturday's Premiership action as Sale won at champions Leicester, while Bath lost again in their derby vs Gloucester.
Recap Saturday's Premiership action as Saracens thumped defending champions Leicester, while London Irish and Sale beat Bath and Exeter respectively.
Gloucester came from 21-0 down to beat Wasps 27-21, while Northampton threatened a similar comeback, but Sale held on to take the points.
Recap Saturday's Premiership action as Saracens came from behind to beat a Quins side missing Marcus Smith; Leicester, Sale and Bristol also won.
Premiership Rugby has taken its first step towards "greater transparency" by publishing a salary cap report for the 2020-21 season.
Leicester Tigers have become the first Premiership club to go through a season on top of the table after every round, as the semi-finals are decided in Round 26.
Manu Tuilagi has been ruled out of England's tour to Australia after undergoing a knee operation.
Exeter's hopes of reaching the Gallagher Premiership play-offs for a seventh-successive season were effectively ended by Bristol on Friday night.
Sale bowed out of the Heineken Champions Cup following a 41-22 quarter-final defeat to Racing 92 in Paris.
We round up all the action from Friday's two Premiership matches, which saw important wins for Northampton and Sale.
Bristol Bears secured a narrow Champions Cup Round of 16 first leg win at Sale Sharks, while La Rochelle won well at Bordeaux-Begles.
Faf de Klerk and Lood de Jager will both leave Sale Sharks at the end of the current Gallagher Premiership season.
Ben Earl scored two tries as Saracens moved a step closer to Gallagher Premiership play-off qualification with victory over Sale.
We look through the potential contenders who the RFU could turn to once Eddie Jones leaves his role as England head coach...
Alex Sanderson has urged the Rugby Football Union to appoint Marc McCall or Andy Farrell as Eddie Jones's England successor.