Defending European Cup champions Toulouse will begin their title defence in Cardiff, in a repeat of the inaugural 1996 final.
Defending European Cup winners Toulouse will face Wasps and Cardiff in 2021/22; Premiership champions Harlequins will play Castres and Cardiff.
Recap Friday's PRO14 Rainbow Cup action as Connacht and Glasgow beat the Ospreys and Leinster, while the Bulls beat the Stormers late on.
Sam Simmonds will start at No 8 for the British and Irish Lions on Wednesday vs the Sharks, while Tom Curry, Adam Beard and Josh Navidi will make debuts.
Jamie Ritchie will captain Scotland for their upcoming summer fixtures, with 17 uncapped players named in their 37-strong squad.
Catch up on the weekend's PRO14 Rainbow Cup action, as Munster and Benetton both won, with the Italians remaining at the top of the table.
The Stormers edged the Lions in South Africa while Cardiff Blues saw off Scarlets and Benetton remain unbeaten after their win against Zebre.
Recap Saturday and Friday's PRO14 Rainbow Cup from both hemispheres, as Leinster, Scarlets, Bulls, Sharks, Munster and Glasgow post big wins.
In the aftermath of Warren Gatland's 2021 British and Irish Lions squad announcement, we look at the winners and losers from the backs.
In the aftermath of Warren Gatland's 2021 British and Irish Lions squad announcement, we look at the winners and losers from the forwards.
Sam Simmonds, who last played for England in 2018, has been included in a 37-man British and Irish Lions squad to face South Africa.
Glasgow Warriors winger and former Scotland international Tommy Seymour has announced his retirement from professional rugby at the age of 32.
Munster, Ospreys and Benetton all kicked off their Rainbow Cup campaigns with wins over Leinster, Cardiff and Glasgow respectively.
Rainbow Cup games between PRO14 clubs and four South African teams have been cancelled, owing to COVID-19 and a lack of permission.
Who are the British and Irish Lions coaches named by Warren Gatland for this summer's tour to South Africa to take on the Springboks?
Three law variations covering red card replacements, captain's challenge and goal-line drop-outs will be used in the inaugural Guinness PRO14 Rainbow Cup.
Curtis Rona's last-gasp try stole 14-man London Irish a dramatic 41-35 victory over Cardiff Blues, while Bath beat Zebre and Glasgow lost to Montpellier.
A round-up of Saturday's PRO14 action as Leinster ended Ulster's push for a place in the final, while Dragons and Glasgow also picked up wins.
Adam Hastings' Scotland return will be further delayed after he was handed a three-game ban for his red card against Leinster on Sunday.
A clinical display from Ulster ensured they kept the pressure on Leinster thanks to a 19-13 victory over Glasgow.