Sam Simmonds will start at No 8 for the British and Irish Lions on Wednesday vs the Sharks, while Tom Curry, Adam Beard and Josh Navidi will make debuts.
Ian Madigan was Ulster's matchwinner at Murrayfield yet again while the Sharks kept their final hopes alive with victory over the Lions.
Catch up on the weekend's PRO14 Rainbow Cup action, as Munster and Benetton both won, with the Italians remaining at the top of the table.
The Stormers edged the Lions in South Africa while Cardiff Blues saw off Scarlets and Benetton remain unbeaten after their win against Zebre.
Cardiff's Owen Lane and Dragons' Rhys Lawrence were shown red cards as the Blues edged their PRO14 Rainbow Cup clash 17-16.
In the aftermath of Warren Gatland's 2021 British and Irish Lions squad announcement, we look at the winners and losers from the backs.
In the aftermath of Warren Gatland's 2021 British and Irish Lions squad announcement, we look at the winners and losers from the forwards.
Sam Simmonds, who last played for England in 2018, has been included in a 37-man British and Irish Lions squad to face South Africa.
We take a look at some of the contenders for the back three in Warren Gatland's British and Irish Lions squad for the tour of South Africa this summer.
We look through the contenders for the 2021 British and Irish Lions half-back positions, and who Warren Gatland might be looking at.
We look through the contenders for the 2021 British and Irish Lions back-row positions, and who Warren Gatland might be looking at.
Munster, Ospreys and Benetton all kicked off their Rainbow Cup campaigns with wins over Leinster, Cardiff and Glasgow respectively.
Rainbow Cup games between PRO14 clubs and four South African teams have been cancelled, owing to COVID-19 and a lack of permission.
Curtis Rona's last-gasp try stole 14-man London Irish a dramatic 41-35 victory over Cardiff Blues, while Bath beat Zebre and Glasgow lost to Montpellier.
Three law variations covering red card replacements, captain's challenge and goal-line drop-outs will be used in the inaugural Guinness PRO14 Rainbow Cup.
Cardiff Blues kept alive their hopes of Champions Cup qualification after fighting back to beat Benetton 29-14 in Italy.
Wales and Cardiff Blues flanker Shane Lewis-Hughes will miss the rest of the season after undergoing shoulder surgery.
Willis Halaholo has reflected on his remarkable rise from Auckland's gang culture to the brink of winning a Six Nations title with Wales.
Cardiff Blues have announced that they will be known as Cardiff Rugby from the 2021-22 season.
Scarlets kept alive their Champions Cup qualification hopes with a bonus-point win over Benetton while Ospreys edged past Zebre.