Top scorer Mauro Icardi watched from the stands as Inter strengthened their grip on third place in Serie A with a 2-1 win over Sampdoria at San Siro.
Gervinho scored twice as Parma came back from 3-1 down to draw 3-3 at Serie A leaders Juventus on Saturday.
Two goals in three minutes helped Genoa secure a 3-1 victory over struggling Empoli in Serie A on Monday.
Napoli cut the gap to Serie A leaders Juventus to six points with a 2-1 win at Lazio, albeit they have now played a game more.
Cristiano Ronaldo scored twice as Juventus sealed a dramatic 2-1 win over Sampdoria.
Cristiano Ronaldo came off the bench to score a late equaliser as 10-man Juventus salvaged a 2-2 draw at Atalanta.
Sassuolo and Fiorentina had to settle for a point each from a thrilling 3-3 draw, while AC Milan and Torino played out a goalless draw.
Cristiano Ronaldo converted a penalty to cap a dominant 3-0 win for Juventus over Fiorentina on Saturday.
Napoli lost further ground on Serie A leaders Juventus after they could only manage a goalless draw at home to bottom club Chievo.
Inter Milan suffered their heaviest defeat of the season by losing 4-1 to Atalanta in Bergamo, days after drawing with Barcelona.
Relegation-threatened Empoli have fired head coach Aurelio Andreazzoli after a run of one win in 11 matches in Serie A this season.
Dries Mertens scored a hat-trick as Napoli trounced Empoli 5-1 to narrow the gap to Serie A leaders Juventus to three points.
Cristiano Ronaldo struck twice, including a thunderous 25-yard drive, as Juventus went seven points clear in Serie A after a 2-1 victory at Empoli.
Lazio left it late but picked up their seventh win in nine league games with a 2-0 victory at Parma.
Roma registered a third straight league win and fourth in all competitions with a 2-0 victory at Empoli in Serie A on Saturday.
Fiorentina shrugged off their midweek defeat to Inter Milan and reclaim third place in Serie A with a 2-0 win over Atalanta.
AC Milan again dropped their seventh point from a winning position when they were held to a 1-1 draw at Empoli in Serie A.
Gonzalo Higuain scored his first Serie A goal for AC Milan but they were held to a 1-1 draw at Cagliari on Sunday.
Napoli missed the chance to go level with Serie A leaders Juventus after tumbling to a 3-0 defeat at Sampdoria.
Big-spending Inter Milan lost 1-0 at Sassulo on Sunday, as Roma and SPAL both chalked up away victories.