Tuesday 24 January 2017 10:42, UK
After a thrilling and closely contested first fight, Carl Frampton will again battle with Leo Santa Cruz for the WBA 'Super' featherweight world title, live on Sky Sports in the early hours of Sunday morning.
Here, we look back at five other iconic boxers to have return fights at the City of Lights...
Where better to start than with the man who made Las Vegas his home and took the glitz and glamour to new levels as he became boxing's and Vegas' main attraction.
'Money', who retired in 2015 with 49 wins from as many fights, was well suited to the extravaganza well associated with the city and would finish a glittering career having won 25 times in Vegas.
His swift, skilful and defensive ability was something to be admired and only twice in his career would an opponent push him so closely that a rematch would be deemed necessary, even by Mayweather himself.
Jose Luis Castillo famously did it and so did Maidana, after a close first fight that many felt could have gone either way. The return would see 'Money' earn over $30m (£24m) in a contest he won comfortably to maintain his welterweight dominance. It would prove to be Maidana's last fight.
Arguably the greatest light-heavyweight of all time, certainly of his generation, Roy Jones Jr had seemed imperious at the 175lbs limit going into his rematch with Antonio Tarver, the only blemish on his record being an avenged disqualification loss to Montell Griffin.
The pair had previously met six months earlier, Jones taking a majority decision victory, and the rematch dubbed 'More than Personal' would once again land at the Mandalay Bay Resort, many expecting a similar or even more conclusive outcome to the first time round.
At his brilliant best, four-weight world champion Jones Jr, who also won heavyweight honours, was virtually untouchable, but Tarver would stun him like no one had ever done before.
The Florida challenger landed a crushing left hook on the exposed chin of Jones Jr in the second round of the contest, a moment that shocked those in attendance and the many watching at home and the defeat would signal the beginning of the end for the great champion.
It is in itself a remarkable story that a Filipino flyweight, with an early knockout defeat on his record, would go on to become boxing's first ever eight-division world champion, but Manny Pacquiao broke down every impeding barrier on his way to greatness and eventual famed idolisation in his native land.
The career of 'Pac Man' is film-worthy, and although Mexican legend Erik Morales would be just one of many great fighters to share the ring with Pacquiao, he is one of only a handful that would create a trilogy of fights with the Filipino that will live long in the memory.
Fighting at super-featherweight, Morales, himself a four-weight world champion, won the first fight between the two and the rematch, ten months later, would again land in the City of Lights.
This time, Pacquiao would claim the victory in spectacular fashion, stopping the Mexican in the tenth round, the first man to ever beat Morales inside the distance. The decisive trilogy-making fight would see Pacquiao go one better and take just three rounds to dispatch of 'El Terrible'.
Frank Bruno had just achieved a lifelong dream, at the third time of asking, by beating Oliver McCall to become the WBC heavyweight world champion, but as he had done earlier in his career, he would once again run into 'Iron' Mike Tyson.
In their first meeting, unified champ and undefeated Tyson stopped Bruno in the fifth round as the self-proclaimed 'Baddest Man on the Planet' continued his commanding supremacy over the heavyweight division.
In the seven years that would pass before a rematch with Bruno, Tyson would be shocked by James 'Buster' Douglas in one of boxing's greatest ever upsets.
1995 would be the year of his comeback, the same year that Bruno got his hands on 'Iron Mike's' old esteemed green belt and Tyson quickly went after the title the following year in a rematch at the MGM Grand. Tyson would win convincingly with a third-round stoppage in what would be Bruno's final bow in the ring.
Having won gold at the 1992 Olympics, Oscar De La Hoya - nicknamed 'The Golden Boy' - rose to stardom and finished his career as a six-weight world champion and one of the sport's highest ever earners.
One of the pound-for-pound best, De La Hoya, like Mayweather, would make the money-making area of Las Vegas his fighting home and his two fights with fellow boxing great, Shane Mosley, would land at the iconic MGM Grand.
The first bout was razor sharp, Mosley winning a contentious split decision to claim the WBC welterweight world title and three years later, De La Hoya sought retribution as they battled once again, this time at the super-welterweight limit.
Despite most feeling De La Hoya had controlled the contest, outlanding his fellow Californian, again Mosley took a controversial decision on the judges' scorecards.
