Robbie Henshaw and George North will miss the rest of the British and Irish Lions tour after suffering injuries during Tuesday's 31-31 draw against the Hurricanes.
Ireland centre Henshaw sustained a torn pectoral muscle, while Wales wing North has a hamstring tear.
Henshaw trudged off midway through the Hurricanes clash and has since had his right arm in a sling.
Both men can expect to be sidelined for some time and will fly home following Saturday's second Test in Wellington.
A short statement from the Lions said: "Robbie Henshaw and George North have been ruled out of the rest of the British & Irish Lions Tour due to injuries suffered against the Hurricanes.
"Henshaw suffered a torn pectoral muscle and North a hamstring tear. Both will return home this weekend for further treatment."
North and Henshaw would have arrived in New Zealand with high hopes of forcing their way into boss Warren Gatland's Test match squad.
However, neither man was able to command selection for last weekend's first Test defeat.
North did claim a try in Tuesday's Hurricanes draw, and only a stray foot in touch denied the Northampton flyer a second score.
But the pair have now suffered premature ends to their tours, and are facing potentially lengthy rehabilitation stints.
Henshaw may require surgery to fix his injury, while North could need at least six weeks' recovery time.