England are only marginal favourites for Saturday's hugely-anticipated showdown with Australia at Twickenham, according to Sky Sports expert Will Greenwood.
Victory over the Wallabies would mean England have won every match they played in 2016 but Eddie Jones goes into the game shorn of key players who have been lost to injuries.
Maro Itoje has missed the autumn international series with a broken hand while No 8 Billy Vunipola is set for three months on the sidelines after suffering a knee injury in Saturday's win over Argentina. Elliot Daly is also out of the squad after his red card against the Pumas.
Australia have beaten France, Scotland and Wales on their tour but lost to Ireland on Saturday and Greenwood says England's mounting injury problems make the match harder to call.
"No Vunipola, no Maro Itoje…some key men in our second row and back row missing," he told Sky Sports News HQ. "Elliot Daly will be missing. England will start favourites but this is margins…5/4 on, something like that.
"Australia come in super form, scoring some great tries - they pulled Wales apart. They scraped home against Scotland and didn't quite manage it against Ireland. But you saw in glimpses…wow, how do England stop this?
"You've got to keep the ball away from their dangermen: Reece Hodge, Bernard Foley, Israel Folau, Tevita Kuridrani - who has scored in every game so far on the tour.
"Then you've got the 'pooper-scoopers' - David Pocock and Michael Hooper, two back-row forwards who have been England's nemesis for so long. It's a cracking Test match.
"It's a great Test match for England to say, 'can we go through a whole year unbeaten and have a proper, proper game of rugby?'"
Wasps star Nathan Hughes and Sale's Josh Beaumont look likely to be fighting it out to replace Vunipola, whose absence is a big blow for England, Greenwood says.
"Vunipola - he was a nominee of the world rugby player of the year," he said. "Billy has been the outstanding No 8 on the planet this year. To miss someone who gives you such delicate hands and awareness…it's a massive blow. He's so different from the other No 8s we have.
"Beaumont's very athletic, very dynamic, a winger's pace, wonderful at the line-out and carry really well…but not a lot of experience. Depending on fitness, the nod may go to Nathan Hughes but I wouldn't be worried if Josh Beaumont got a run out."
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