Marland Yarde has been dropped by Harlequins for their match against Wasps due to an "internal disciplinary matter".
The club revealed the news when announcing their side for the trip to the Ricoh Arena to play Wasps in the European Rugby Champions Cup on Sunday.
Yarde was replaced in the starting XV by Charlie Walker, and was not named on the replacements' bench.
It is unclear what the matter in question relates to. Harlequins say they will be making no further comment.
Yarde has scored four tries in seven appearances for his club this season.
Last month, he was included in the England training camp by Eddie Jones ahead of the autumn internationals.