Scotland flanker Hamish Watson has been recalled to the starting XV to face England in the Six Nations on Saturday.
The Edinburgh back-rower started Scotland's first two games against Ireland and France, before being named on the bench for the win over Wales on February 25.
However, his replacement John Hardie has been ruled out of the remainder of the tournament with the knee injury suffered against Wales.
Otherwise, it is the same starting line-up which beat Wales 29-13 at Murrayfield. The uncapped Cornell Du Preez takes Watson's place on the bench.
A victory for Scotland this weekend would be their first at Twickenham since 1983 and earn them their first Triple Crown success since their Grand Slam triumph in 1990. They last beat England in 2008.
England are two games away from a second successive Grand Slam and go into the Calcutta Cup clash seeking a record-equalling 18th straight Test win.
Scotland head coach Vernon Cotter said: "There's a lot to play for and several reasons why we should be able to get up for this game.
"We've rested, recovered and prepared as best we can for this game. We've asked some questions of ourselves and the areas we think we can improve and we're confident we can play better as a team. That's our next challenge, to step that up.
"The challenge is for us to combine the best parts of our performances so far in this campaign in to one excellent performance at Twickenham this Saturday.
"We'll need that to put us in a position to win this game and will enjoy the challenge of doing that against an England team that hasn't lost in a while."
Scotland: 15 Stuart Hogg, 14 Tommy Seymour, 13 Huw Jones, 12 Alex Dunbar, 11 Tim Visser, 10 Finn Russell, 9 Ali Price; 1 Gordon Reid, 2 Fraser Brown, 3 Zander Fagerson, 4 Richie Gray, 5 Jonny Gray, 6 John Barclay (c), 7 Hamish Watson, 8 Ryan Wilson.
Replacements: 16 Ross Ford, 17 Allan Dell, 18 Simon Berghan, 19 Tim Swinson, 20 Cornell Du Preez, 21 Henry Pyrgos, 22 Duncan Weir, 23 Mark Bennett.