Vern Cotter has made three changes to his Scotland line-up for Saturday's clash with Ireland in Dublin.
Duncan Weir replaces Finn Russell at stand-off after his Glasgow team-mate was ruled out with concussion in last weekend's 29-18 win over France.
With Jonny Gray also unavailable after suffering a torn pectoral muscle against Les Bleus, Tim Swinson steps up from the bench to partner Gray's brother Richie in the second row.
Ryan Wilson also returns to the starting XV in place of Josh Strauss, who drops to the bench despite a decent display against Guy Noves' men.
Weir was absent from the Scotland squads that defeated Italy and France and last started against South Africa in the World Cup.
Cotter said: "We were pleased with our sustained effort against France. I was happy with the way we adapted to losing Finn so early in the game. The team came together and was rewarded for their endeavour with the end result.
"The challenge for us now is to keep constructing our game and enjoy the last coming together of the championship in a Scotland jersey, against an Ireland team full of confidence after a convincing win over Italy."
Cotter has made two further changes to the replacements, with Rob Harley taking the place on the bench place vacated by the promoted Swinson, while Henry Pyrgos has been named as replacement scrum-half for what could be his first Scotland appearance since his post-World Cup wrist surgery.
Scotland: 15 Stuart Hogg, 14 Tommy Seymour, 13 Duncan Taylor, 12 Alex Dunbar, 11 Tim Visser, 10 Duncan Weir, 9 Greig Laidlaw, 1 Alasdair Dickinson, 2 Ross Ford, 3 Willem Nel, 4 Richie Gray, 5 Tim Swinson, 6 John Barclay, 7 John Hardie, 8 Ryan Wilson
Replacements: 16 Stuart McInally, 17 Rory Sutherland, 18 Moray Low, 19 Rob Harley, 20 Josh Strauss, 21 Henry Pyrgos, 22 Peter Horne, 23 Sean Lamont