Manu Tuilagi has been included in England's matchday squad for their Six Nations clash with Wales on Saturday.
Leicester centre Tuilagi could bring to an end his injury-enforced 20-month international absence if he comes off the bench at Twickenham.
Tigers' director of rugby Richard Cockerill has voiced concerns that Tuilagi, who has struggled with groin and hamstring problems, is not ready for a return to the international stage.
But England head coach Eddie Jones disagrees and has included him in his squad, with Alex Goode the man to make way.
Wasps back Elliot Daly is retained for the penultimate round of the competition, while his club team-mate Joe Launchbury returns after sitting out the 21-10 win over Ireland with a hamstring injury.
Northampton prop Kieran Brookes comes in to replace fellow Saints player Paul Hill in the 24, while Luke Cowan-Dickie of Exeter remains with the squad as cover for Jamie George at hooker.
"Jamie George sustained an injury to his arm during this afternoon's [Tuesday's] training so Luke Cowan-Dickie remains with the squad as cover while Jamie undergoes further medical assessments," said England head coach Eddie Jones.
England remain on course for the Grand Slam, having won their opening three matches against Scotland, Italy and Ireland.
ENGLAND SQUAD:
Forwards: Kieran Brookes, Dan Cole, Luke Cowan-Dickie, Jack Clifford, Jamie George, Dylan Hartley, James Haskell, Maro Itoje, George Kruis, Joe Launchbury, Joe Marler, Chris Robshaw, Billy Vunipola, Mako Vunipola
Backs: Mike Brown, Danny Care, Elliot Daly, Owen Farrell, George Ford, Jonathan Joseph, Jack Nowell, Manu Tuilagi, Anthony Watson, Ben Youngs
Eddie Jones names his England team to play Wales on Thursday. Watch Sky Sports News HQ from 10am to see the announcement.