We look into the stats and team news ahead of all six Gallagher Premiership encounters this weekend...
Saturday
Bath vs Exeter Chiefs (3pm)
Sam Underhill makes his comeback for Bath after recovering from a hip injury. Beno Obano returns from England duty to start at loosehead prop. Wales back row Taulupe Faletau starts.
Scotland internationals Jonny Gray and Stuart Hogg are present in Exeter's starting XV. Wales prop Tomas Francis is on the Chiefs' bench where he is joined by Jannes Kirsten, who has recovered from a fractured eye socket.
Last season: Exeter 57 Bath 20, Bath 13 Exeter 10
Last six league matches: Bath L L L W W W Exeter L W W W L L
Top try scorers: Zach Mercer (Bath) 3; Sam Simmonds (Exeter) 12
Top point scorers: Rhys Priestland (Bath) 91; Sam Simmonds (Exeter) 60
Wasps vs Gloucester (3pm)
Wasps centre Malakai Fekitoa has recovered from a hamstring injury to start as one of four changes made by the Premiership runners-up with full-back Rob Miller, flanker Thomas Young and hooker Gabriel Oghre also returning.
Wales star Louis Rees-Zammit has been rested by Gloucester. George Barton makes his first Premiership start at fly-half, while Argentina hooker Santiago Socino debuts for the club.
Last season: Wasps 39 Gloucester 22, Gloucester 25 Wasps 9
Last six league matches: Wasps W L L W L L Gloucester L L L L L W
Top try scorers: Paolo Odogwu (Wasps) 5; James Hanson (Gloucester) 3
Top point scorers: Lima Sopoaga (Wasps) 48; Billy Twelvetrees (Gloucester) 72
Worcester Warriors vs Bristol Bears (5.15pm)
Worcester captain Ted Hill has recovered from a stiff back to make his comeback as one of three changes that also see hooker Beck Cutting and wing Perry Humphreys involved in the starting XV.
Bristol have rested full-back Charles Piutau so Henry Purdy starts at 15. Callum Sheedy is present at fly-half fresh from helping Wales beat England. Lock Dave Attwood is back from injury.
Last season: Worcester 13 Bristol 36, Bristol 13 Worcester 10
Last six league matches: Worcester L L L L L L Bristol W W L W D W
Top try scorers: Nick David (Worcester) 3; Bryan Byrne (Bristol) 5
Top point scorers: Duncan Weir (Worcester) 24; Ioan Lloyd (Bristol) 42
Sunday
Harlequins vs Northampton Saints (3pm)
Harlequins make six changes, among them the return of scrum-half Danny Care, full-back Mike Brown and centre Joe Marchant. Hooker Scott Baldwin, flanker Archie White and No 8 Alex Dombrandt are restored up-front.
Northampton make four changes with wing Ollie Sleightholme and centre Fraser Dingwall starting behind the scrum and prop Paul Hill and lock Alex Hills featuring in the pack.
Last season: Harlequins 30 Northampton 17, Northampton 40 Harlequins 22
Last six league matches: Harlequins D W W W W L Northampton L W W W W L
Top try scorers: Alex Dombrandt (Harlequins) 6; Shaun Adendorff (Northampton)
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Top point scorers: Marcus Smith (Harlequins) 140; James Grayson (Northampton).