Test your knowledge of the history between England and the Springboks ahead of Saturday's clash, live on Sky Sports Action from 2pm.
These two sides are very familiar with each other after England's tour to South Africa earlier in the year, which ended in a 2-1 series win for Rassie Erasmus' side.
From an English perspective, the conversation leading into this match has been dominated by injuries. The home team must face the Boks without the likes of Mako and Billy Vunipola, Joe Launchbury and Chris Robshaw.
The Springboks may well have player-availability issues to contend with for this Test match too, but regardless, they will arrive in south west London with their usual intensity and purpose.
Over the years, there have been some quite outstanding matches between these two teams. Test your knowledge of that history by taking our quiz...
#Followtherose this autumn with all of England's Tests live on Sky Sports throughout November. The action starts on Saturday November 3 against South Africa before clashes against New Zealand, Japan and Australia.