Scotland have added Edinburgh winger Dougie Fife to their squad for the tour of the Americas following injury to Lee Jones, who hurt his knee against Canada.
Glasgow Warriors winger Jones suffered the injury as Scotland won 48-10 in Edmonton and he will have to return home on Tuesday.
The Scottish Rugby Union said in a statement on Monday: "Jones travelled with the squad to Houston, Texas, yesterday.
"Further medical assessment confirmed that he will play no further part in the tour and will return home tomorrow to the care of his club's medical team for ongoing treatment."
Jones was forced off against Canada after 30 minutes of the game, and Fraser Brown also left the pitch with a rib injury as the Scots powered past Canada with replacement hooker George Turner becoming the first Scotland player in 11 years to score a hat-trick of tries.
Scotland's second game of the tour sees them take on the United States in Houston next weekend before facing Argentina in Resistencia the following Saturday.
Scotland head coach Gregor Townsend said: "It was a Test match, both teams were physical. Canada did a lot of good things, they were dangerous when they got the ball.
"That is the difference between training and playing in a game, especially with a team that has never played before - some players who have never played for Scotland and some who have only got to know their team-mates a few weeks ago.
"While there were some frustrations with parts of the game, it was great that we got over that. We worked hard and came away with a good win.
"There are a few aspects I don't want to share where we have to improve. The USA [who they play next Saturday] seem a really good team on form. They are a team going places and will be a big threat."