Warrington will be without full-back Stefan Ratchford for the start of the 2017 Super League season.
Ratchford, 28, made his England debut in last month's win over France in Avignon but picked up a knee injury while training with the England squad during the Four Nations Series.
The Wolves have revealed Ratchford, who missed the first month of their 2016 campaign with a shoulder injury, suffered a lateral meniscus tear and is not expected to be fit until March.
Warrington will also be without second rower Ben Currie until June after he underwent a knee re-construction.
They have also announced that captain and England prop Chris Hill has had surgery to correct hernia and shoulder problems after England's Four Nations campaign was brought to an end by Australia last Sunday.