There's plenty at stake in Thursday night's Super League encounter. Wigan need a win at the DW Stadium to push them up the table as they prepare for the Super 8s.
Warrington's own Super 8 chances could end this weekend if results go against them. Here's three head-to-heads that might decide it:
Sam Tomkins v Stefan Ratchford
It's good to see Sam Tomkins back in action. He returned to the pitch against this week's opponents in the Challenge Cup, knocking over a crucial drop goal as the Warriors secured a semi-final spot.
Three Super League games have followed, with Tomkins scoring his first try of the season in the win over Catalans. It's been a difficult 2017 for Wigan, but they're still in contention and need to put some form together to make a top-four spot. And the return of players like Tomkins will be crucial. It's not worked out as he planned since his return from the NRL, and with the World Cup around the corner, now's the chance to make up for lost time.
It seemed Stefan Ratchford had finally found a permanent position this season. He started his first ten Super League games in 2017 at full-back. But Ratchford's versatility is what makes him such an important player. He switched to centre and stand off for three games recently as Kevin Penny and Will Dagger both slotted in.
But in the win over Leigh last week, Ratchford returned to the number one position. Ratchford has actually only scored one try all season, but he's second in the assists chart with 11, only behind Kurt Gidley.
He's notched up some serious yardage this season, carrying 171 times for 1573 metres at an impressive 9.20m a run. Don't forget Ratchford is the man in possession of the England full-back shirt having started and scored against Samoa. Will he hold onto that place?
Joe Burgess v Tom Lineham
Joe Burgess is another player who's suffered an injury hit season. He's missed seven of Wigan's 21 Super League games since his return from the NRL. But check out his try-scoring record. Burgess has crossed 16 times in 14 games, a strike rate that's seen him soar to second in the Warriors' scoring charts, four behind Liam Marshall. And that includes five in his last two games; two against Widnes and a hat-trick against Catalans.
Burgess is excellent with the ball, making 1157 metres at an average of 8.26m a carry. And that includes 11 clean breaks and 23 tackle busts. Warrington will have to be wary of his try-scoring prowess on Thursday.
Tom Lineham has shown more of what he's capable of this season. Since his switch to Warrington from Hull FC, his form has had its ups and downs.
The winger has provided a steady rate of scoring this campaign. Lineham is comfortably Warrington's top scorer, crossing 16 times so far in the Super League, seven more than their next best Ryan Atkins.
He's only not scored in four of the 17 league games he's played this season. However, the winger's best showing came last time out, crossing four times in the 50-10 hammering of Leigh. And if he carries on at this rate, Lineham will go past the 25 league tries he scored in 2015 for Hull FC, the campaign that earned him the switch to the Wolves. Don't bet against him crossing against Wigan.
John Bateman v Jack Hughes
Another Wigan player, another long spell out with injury. It's been the story of their season. John Bateman had to have shoulder surgery after the World Club Challenge win over Cronulla.
But he, like Tomkins, returned for the Challenge Cup win over Warrington and has started the three Super League games since. It's a massive boost for Wigan's season.
Bateman scored against both Warrington and Huddersfield and possesses the all-round game that makes him a shoo-in for England if fit. His three league appearances have already yielded two try assists, 96 tackles and 48 carries for an average gain of 7.02m a drive. Expect him to keep stepping up the gears as the season comes to a close.
The big news in the Warrington pack is that Ben Currie is back in the 19-man squad for the first time this season. Whether he's fit to play yet is unclear. But Warrington will have to rely on the likes of Jack Hughes for the time being.
Hughes is a man every pack needs. He does the dirty work. And the second rower is Warrington's top tackler for the season, with 571 hits so far, just five more than Daryl Clark. But Hughes also puts his hands up in attack.
He's carried the ball the second most of any Warrington player (234), just behind Chris Hill. Hughes has made a solid 1607m from those carries at an average gain of 6.87m a drive. Hughes is also surprisingly high up the try-scoring charts too, crossing five times in 2017, already his best tally of any season. Hughes is a former Wigan player of course, so expect him to raise his game on Thursday.