Manchester City, Arsenal and Glasgow City have learned their Women’s Champions League opponents after the last-16 draw was made.
Man City host Atletico Madrid, which will see England's Toni Duggan come up against her former side after she moved to the Spanish capital from Barcelona in the summer. Atletico are captained by the Netherlands' World Cup finalist and Best FIFA goalkeeper winner Sari van Veenendaal.
Steph Houghton, Ellen White, Jill Scott, Demi Stokes, Ellie Roebuck, Keira Walsh, Karen Bardsley, Gemma Bonner and Georgia Stanway are among the English City players who may face Van Veenendaal and international team-mate Duggan.
Arsenal, meanwhile, will face Slavia Prague, with the first leg away from home, as the Women's Super League champions begin their European campaign, with a trio of Lionesses - Leah Williamson, Jordan Nobbs and Beth Mead - looking to bring more silverware to north London.
Glasgow City have been handed a tie against Danish side Brondby, again with the first leg at home, which may feature Glasgow's Scotland internationals Lee Alexander, Hayley Lauder, Joanne Love, Leanne Crichton, Rachel McLauchlan and Nicola Docherty.
Lucy Bronze's Lyon, who won the Champions League last season - and also have England stars Nikita Parris and Alex Greenwood on their books - face Fortuna Hjorring of Denmark in the round of 16.
Elsewhere in the draw, last season's Champions League finalists Barcelona take on FC Minsk, while Bayern Munich face a long journey for their away leg to play Kazakhstan's BIIK Kazygurt.
Wolfsburg come up against FC Twente, seeing Dominique Bloodworth face Netherlands international team-mate Renate Jansen. Paris Saint-Germain have been drawn to play Icelandic team Breidablik.
Women's Champions League last-16 draw
Glasgow City v Brondby
Barcelona v FC Minsk
BIIK Kazygurt v Bayern Munich
Lyon v Fortuna Hjorring
Paris Saint-Germain v Breidablik
Wolfsburg v FC Twente
Slavia Prague v Arsenal
Manchester City vs Atletico Madrid
Ties to be played October 16/17 and October 30/31.