Substitute Barry Corr scored twice to inspire Cambridge to their first ever Football League double over Stevenage.
The last time the U's beat Stevenage twice in a season was a decade ago in what is now the National League.
Striker Corr has now scored 16 goals in 36 league appearances for the club after he helped interim head coach Joe Dunne pick up his first victory on the road since his first game in charge - a 3-2 win at Chesterfield in February.
Early on, Stevenage missed a great chance when Danny Newton's header was kept out by David Forde.
Down the other end, Tom King made a great one-on-one save to keep Billy Waters from opening the scoring.
On the stroke of half-time, Alex Revell squandered two chances to give the Robins the lead and they were made to pay after the break by Corr's brace.
Corr had only been on the pitch four minutes before heading home with his first touch on 54 minutes.
The second seven minutes from time was a great team move, with Corr converting Brad Halliday's cutback.