West Ham's Aaron Cresswell has received his first England call-up and Sunderland goalkeeper Jordan Pickford has also been drafted into Gareth Southgate's squad for the forthcoming matches against Scotland and Spain.
The pair will join up with the senior team at St George's Park on Tuesday following the withdrawals of Leicester City midfielder Danny Drinkwater and Southampton goalkeeper Fraser Forster through injury.
England face Scotland in a World Cup Qualifier at Wembley on Friday, November 11 before hosting Spain at the same venue on November 15.
Left-back Cresswell, who began his career at Tranmere Rovers, joined West Ham from Ipswich two years ago and has gone on to make 77 appearances for Slaven Bilic's side.
Cresswell has played just three league matches this season, having struggled with a knee injury, and was then sent off on his return at Crystal Palace before completing 90 minutes against Everton and Stoke.
He told his club's website: "I am delighted to receive a call-up and it's a very proud moment for me and my family.
"I just want to enjoy the experience and do my best in training and if I can do that, then I hope I can achieve my dream. I can't thank the club enough, particularly the fans who have been different class to me since I arrived."
Sunderland keeper Pickford made his debut for the England U21s in September 2015 and received his first senior call from Southgate to replace the injured Tom Heaton for the qualifier against Slovenia last month.