West Ham stunned in-form Tottenham by coming from behind to win 3-2 in a dramatic Carabao Cup fourth-round tie at Wembley.
After a much-changed Spurs side coasted into a two-goal half-time lead, their London rivals rallied with three goals inside 15 second-half minutes to progress to the quarter-finals.
Moussa Sissoko and Dele Alli had made it 2-0 at the interval, with this the first of two games needed for Slaven Bilic to save his job at the Hammers.
But Andre Ayew scored twice to haul the Hammers level on the hour before Angelo Ogbonna rose from a corner to head home the winner with 20 minutes remaining.
Bilic came into the tie under immense pressure to keep his job and his fate looked ominous as Tottenham bossed the first half without a string of key players.
Kane, Hugo Lloris, Serge Aurier and Jan Vertonghen were not in the matchday squad and Christian Eriksen was dropped to the bench, but Mauricio Pochettino's side looked unaffected as they hit their opponents on the counter-attack for Sissoko's opener.
Alli almost fired the second when he forced Adrian to save with a back-post header but eventually sealed his second goal in as many games with a curling shot that hit the back of Declan Rice and found the net.
West Ham were abject in the first half but capitalised on a creeping sluggishness in Spurs when Edmilison Fernandes' shot was parried straight to Ayew to pull one back.
Ayew went close with a header immediately afterwards and then equalised on the hour-mark from Manuel Lanzini's low cross into the six-yard box.
And the Hammers sealed the shock of the fourth round when Ogbonna steered his header into the bottom corner with 20 minutes remaining.
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- West Ham have reached quarter-final stage of the League Cup in consecutive campaigns for the first time since 1980-81, the same season they beat Tottenham en route to a final defeat by Liverpool.
- Spurs, meanwhile, have now failed to reach the quarter-final in each of the last three seasons in the League Cup, with all three defeats coming against Premier League opposition (Arsenal in 2015/16, Liverpool in 2016/17 and West Ham in 2017/18).
- The Hammers scored three goals away from home for the first time since February in all competitions (1-3 victory at Southampton in the Premier League).
- Alli (20) is one of only four Premier League players to have scored 20+ goals in all competitions in 2017, following Harry Kane (38), Romelu Lukaku (27) and Sergio Aguero (25).
- Since making his debut for the club in August 2016, Andre Ayew has been directly involved in more goals than any other West Ham player (15 - 10 goals, 5 assists).
- After failing to score in his first 43 appearances for Spurs, Moussa Sissoko has now scored two in his five outings since.
Man of the Match - Andre Ayew
When West Ham and Slaven Bilic needed a performance, Andre Ayew was the man who stood up to be counted. His opportunistic first goal was the lifeline the Hammers needed just as their season appeared to be stooping to new lows. He added the finishing touch to a fine move as West Ham drew level, laying the foundation for Ogbonna to complete a remarkable turnaround.
What's next?
Spurs travel to Manchester United for Saturday's early kick-off, live on Sky Sports Premier League, before West Ham make the trip across London to Crystal Palace at 3pm.