Juventus extended their lead at the top of Serie A to seven points with a comfortable 2-0 victory at Crotone on Wednesday.
Mario Mandzukic opened the scoring for the visitors on the hour mark before Gonzalo Higuain doubled their advantage with 16 minutes remaining.
Crotone, who remain nine points from safety, put up an able resistance against the champions but after Mandzukic broke the deadlock the victory never appeared in doubt.
The win marked a fourth consecutive triumph for Massimiliano Allegri's side who have now established clear breathing space between themselves and their rivals as they battle to defend their league crown.
AC Milan ended a three-match losing streak in remarkable fashion as they won 1-0 at Bologna despite having two players sent off.
Centre-back Gabriel Paletta was dismissed in the first half and Juraj Kucka followed just before the hour mark.
Milan also saw Alessio Romagnoli forced off with injury after half an hour.
But the visitors snatched victory when Everton loanee Gerard Deulofeu crossed for Mario Pasalic to tap in the winner in the last minute.