Nantes claimed only their fourth Ligue 1 win of the season after a goal in each half saw off Angers at Stade Jean-Bouin.
Belgian international Guillaume Gillet fired Nantes into an 18th-minute lead when he struck with a right-footed shot from outside the box.
And the visitors then added a second just three minutes after the break when 19-year-old midfielder Amine Harit underlined Nantes' domination.
Angers could make little headway in the contest, and with Nantes rediscovering a goal touch that had recently deserted them, the home side could find no way back on a frustrating night for them.