Celtic travel to McDiarmid Park on Sunday to St Johnstone as they look to extend their unbeaten domestic record to 29 matches.
The last match the Premiership champions lost was away to Tommy Wright's men in a 2-1 defeat back on the 11th May.
St Johnstone themselves have won two in a row and are level on points with Hearts in fourth and 10 points ahead of sixth placed Motherwell.
Motherwell will be hoping to close the gap on St Johnstone and Hearts when they welcome Ian Cathro's side to Fir Park in Saturday's early kick-off.
Aberdeen missed the chance to leapfrog Rangers on Wednesday when they went down 1-0 to Celtic and remain a point behind the Ibrox club with a game in hand.
Partick Thistle missed a chance to go into the top-six on Wednesday after their 1-0 loss at home to St Johnstone.
Hamilton recorded a much needed 3-0 win against bottom club Inverness on Tuesday and can go level with ninth-placed Kilmarnock if they come out on top against Lee Clark's men tomorrow.
It's 12th v 10th when Inverness host Dundee at 3pm. Inverness haven't won in 12 Premiership fixtures and are three points adrift at the bottom of the table.
Ross County travel to Ibrox tomorrow just one point from the top six, but they are also just three points clear of the relegation play-off spot.
Motherwell v Hearts - Saturday 12.15pm
Andy Walker's prediction:
Motherwell 0-2 Hearts
Key player: Esmael Goncalves
Impressive debut against Rangers, should add more punch to Hearts attacking options.
Ian Crocker's prediction:
Motherwell 1-1 Hearts
Key player:Jamie Walker
Fresh from two goals against Rangers and usually in a menacing mood.
Aberdeen v Partick Thistle - Saturday 3pm
Andy Walker's prediction:
Aberdeen 2-0 Partick Thistle
Key player: Ryan Christie
Can the on loan Celtic man get the game-time he's looking for at Pittodrie?
Ian Crocker's prediction:
Aberdeen 2-0 Partick Thistle
Key player: Niall McGinn
A man in the zone at the moment. So much to offer.
Hamilton Accies v Kilmarnock - Saturday 3pm
Andy Walker's prediction:
Hamilton Accies 1-1 Kilmarnock
Key player: Kris Boyd
Striker still has it, his goal after 10 secs proving he's lost none of his sharpness.
Ian Crocker's prediction:
Hamilton Accies 1-2 Kilmarnock
Key player: Conor Sammon
Having struggled for goals at Hearts, what's the betting he scores?
Inverness CT v Dundee - Saturday 3pm
Andy Walker's prediction:
Inverness CT 1-0 Dundee
Key player: Owain Fon Williams
Welsh keeper can keep a fragile Caley Thistle squad in the game with vital saves.
Ian Crocker's prediction:
Inverness CT 1-0 Dundee
Key player: Gary Warren
A natural leader and it's time for Caley Thistle to dig deep.
Rangers v Ross County - Saturday 3pm
Andy Walker's prediction
Rangers 2-1 Ross County
Key player: Lee Wallace
Rangers need strong, experienced players to cope with the pressure at this difficult time.
Ian Crocker's prediction:
Rangers 2-1 Ross County
Key player: Lee Wallace
The captain often shows the way forward.
St Johnstone v Celtic - Sunday Live on Sky Sports 5 from 12pm
Andy Walker's prediction:
St Johnstone 1-2 Celtic
Key player: Craig Gordon
A boost for every Celtic fan that Chelsea were unable to sign him in transfer window.
Ian Crocker's prediction:
St Johnstone 2-2 Celtic
Key player: Steven McLean
Scored in his last three starts against Celtic.