Liverpool are to play Spanish champions Barcelona at Wembley on Saturday August 6.
The match, which will be part of the International Champions Cup, will kick-off at 5pm.
The Reds are one of 10 teams competing in the tournament and will play two matches in California in July before heading back to the UK to face Barcelona at the national stadium.
They play Chelsea at the Pasadena Rose Bowl on July 27 followed by a clash with AC Milan at Levi's Stadium in Santa Clara on July 30.
Liverpool ambassador Gary McAllister was at Wembley for the announcement of the match against Barcelona, who are likely to feature former Reds forward Luis Suarez, and is already looking forward to the game.
He said: "What an incredible game to round off such a high-profile tournament - and all set under the iconic Wembley arch.
"I'm sure this game will be a great spectacle for Reds fans and football fans in general. I can't wait."
Charlie Stillitano, chairman of tournament organisers Relevent Sports, said: "Barcelona and Liverpool are two of the biggest football clubs in the world.
"The ability to have these two powerhouse clubs compete is what the ICC is all about and truly an honour. Bringing these clubs and the ICC to Wembley Stadium is an incredible mark of the growth of tournament in only four years."