Pep Guardiola faces a defensive headache as Manchester City welcome Southampton in the Premier League on Nissan Super Sunday.
Pablo Zabaleta has been ruled out of the match, live on Sky Sports 1, and with fellow right-back Bacary Sanga also suffering with a hamstring injury, the manager will be facing a tough decision about who to play in the position.
City will be looking to bounce back from their 4-0 loss to Barcelona in the Champions League on Wednesday, having lost one and drawn one of their last two league fixtures.
Southampton also suffered a European defeat in midweek - losing 1-0 to Inter Milan in the Europa League - but are unbeaten in their last four Premier League outings.
Team news
Sergio Aguero is expected to return to the starting XI after starting on the bench at the Nou Camp in a tactical move by Guardiola, with Vincent Kompany not fit enough to make the bench on Wednesday.
Southampton striker Shane Long will not be available after suffering a hamstring injury during Thursday's defeat at Inter Milan and although Saints have yet to discover the extent of the damage, he will not be available against City.
Ryan Bertrand, Matt Targett and Cedric Soares will be assessed after missing the trip to Italy while Nathan Redmond returns to the squad after being rested.
Match stats
City had won four in a row in the Premier League against Southampton before their 4-2 loss to the Saints in May.
Southampton have lost their last five league visits to the Etihad, last beating City on their own patch in April 2004. Paul Sturrock's side won 3-1 thanks to James Beattie and two from Kevin Phillips.
Kelechi Iheanacho scored twice in City's 4-2 loss to Southampton in May, his most recent brace for the club.
Shane Long has scored four Premier League goals against Manchester City, only against Aston Villa does he have more (6).
Saints have kept two just clean sheets in their last 10 Premier League away games, however those shutouts have come on their last two away trips; they last kept three consecutive away clean sheets in the top-flight back in February.
Guardiola hasn't gone three games without a league win since the end of the 2014/15 season (three losses with Bayern after they had won the league).
Dusan Tadic has created 28 chances in the Premier League this season, more than any other player, yet hasn't provided an assist for a teammate yet.
David Silva has provided more Premier League assists than any other player in the competition since his debut (59).
Southampton have collected 51 points in 2016, two more than Manchester City have in the calendar year (49).
Aguero hasn't gone three Premier League games without a goal since December 2015.
Merson's prediction
This is a difficult game for City. They had their confidence shot at the Nou Camp, but I think they'll just get a result here.
I agree that City are short of the players Pep Guardiola wants. They've got to change their style of play slightly, you can't keep rolling out from the back, because teams will just close you down.
Also, you put a bit of a pressure on the goalkeeper. I want a goalkeeper who is going to make a save, not spray it around the pitch all day.
Southampton will be a threat, and will give them a really good game, but I'm going with City.
PAUL PREDICTS: 2-1 (7/1 with Sky Bet)
Betting
City can be backed as the odds-on favourites at 1/2 with Sky Bet to beat Southampton in Super Sunday's opening match in front of the Sky Sports cameras. Saints are 5/1 outsiders to extend their unbeaten run to eight matches with victory at the Etihad Stadium and the draw is priced up at 100/30.
Aguero dropped to the bench for City's Champions League defeat at Barcelona in midweek but the Argentina international heads Sky Bet's first goalscorer prices at 3/1. The top Saints contender is the in-form Charlie Austin at 8/1.