Manchester United will be looking to bounce back from their 2-1 derby defeat to City and Europa League disappointment when they travel to Watford on Sunday.
Mourinho's side have suffered a bad week with defeat at home to their city rivals before going down to a 1-0 defeat against Feyenoord in Rotterdam on Thursday.
United will be looking to get back on track against the Hornets in the midday kick-off on Sunday.
Watford have four points on the board from their opening four games including a stirring comeback from 2-0 down to beat West Ham 4-2 in their last league outing.
United's visit is the latest in a run of tough fixtures at Vicarage Road where Walter Mazzarri's side have already lost to Premier League big boys Chelsea and Arsenal.
Team news
Mazzarri is expected to retain much of the starting XI that won at the London Stadium.
Younes Kaboul faces a late fitness test, as does Sebastian Prodl, who replaced him as a substitute.
Stefano Okaka also made his debut, coming on as substitute, but has been ruled out for the next month with a hamstring injury.
Wayne Rooney, Antonio Valencia and Luke Shaw return to Mourinho's matchday squad.
The trio were rested for Thursday's Europa League tie at Feyenoord, with the latter not risked after complaining of a tight hamstring following the derby defeat to Manchester City.
Centre-back Eric Bailly will be assessed after receiving a knock during the midweek loss in Holland, while Henrikh Mkhitaryan (thigh) is set to join Phil Jones (knee) on the sidelines.
Match stats
Watford have lost each of their last nine league meetings with United, including the previous six in the Premier League.
United's last league defeat against Watford came in September 1986, two months before Sir Alex Ferguson was appointed manager of the club.
Ibrahimovic has scored four goals in his first four Premier League games for Manchester United.
The Red Devils haven't won three consecutive Premier League away games since a run of four ended in April 2014, under David Moyes' management.
Watford have never lost three consecutive home Premier League games before.
Merson's prediction
The win over West Ham was a big result for Watford, and not just because Troy Deeney and Odion Ighalo got back on the goal trail.
Etienne Capoue has made a big change from the end of last season. They were getting predictable because it was almost like they didn't have a chance when Deeney and Ighalo weren't at it, but Capoue is giving them a little bit extra now.
Manchester United's confidence will be knocked after losing in their own backyard against their arch enemy, who didn't even have their best player. That was a major blow.
Watford are the league's entertainers at the moment - there's always goals when you go and watch them play.
PAUL PREDICTS: 2-2 (Sky Bet odds 16/1)