Yorkshire pulled four players out of Monday night's Vitality Blast match against Lancashire at Headingley due to concerns over coronavirus.
Yorkshire announced on Twitter that the quartet, including David Willey and Tom Kohler-Cadmore, would not take part in the North Group Roses game.
Yorkshire said: "Matthew Fisher, Tom Kohler-Cadmore, Josh Poysden and David Willey have been withdrawn from tonight's squad in accordance with COVID guidance.
"The club are awaiting results of a COVID test which will determine future availability."
After Yorkshire's subsequent defeat to Lancashire, head coach Andrew Gale said: "We were hoping one of the four lads would have their test back, which would have enabled the rest of them to play.
"They were sat outside the ground until 5.30pm waiting on a text, but unfortunately it didn't come. To have the heart of your team ripped out was always going to make it tough tonight.
"I'm hopeful that a text will come (Tuesday) morning and they'll be back in the mix on Wednesday (for the game against Durham).
"With the guidelines in place, the physios and club doctor said they couldn't take part in the game unless that one person tested negative. Unfortunately, it didn't come through.
"I fully expect it to be negative, but you just don't know. You have to be careful. I don't really want to get into who it was. It's just disappointing we had those four lads out.
"Only one player has been tested. The family member had symptoms, but that player has come into contact with the other players outside our cricket bubble."
Watch the return Roses match between Lancashire and Yorkshire, at Emirates Old Trafford, live on Sky Sports Cricket from 6.30pm on Thursday.