Joe Cordina is the latest British boxer to fall before the Olympic quarter-final stage as he was outpointed by fifth seed Hurshid Tojibaev.
Cordina arrived in Rio boasting a European Championship lightweight gold medal and ranked eighth in the world but was unable to match the physicality of Tojibaev, who went through 28-28 29-27 29-27 despite a point deduction.
Cordina began on the back foot and looked keen to exhibit his superior movement, keeping his hands low. Tojibaev was in no mood to allow him the chance to show off, though, and duly uncorked a solid opening left hook.
The Welshman, 24, was looking to counter-punch at every opportunity and was boxing with more success in picking several sharp jabs to catch his opponent lunging in, but the momentum swung again at the end of the session when Tojibaev landed with both hands to pinch the opener.
The second was more dramatic and began with Tojibaev hunting down his foe and attempting to drag him into some heavy exchanges. He was having success in doing just that when he was penalised for a low blow and despite struggling to match Tojibaev's physicality, Cordina was granted a share of the round on the scorecards.
The final session was more of the same as Tojibaev continued to initiate the action, and Cordina sustained a pair of decent left hooks in the first half of the round before Tojibaev stepped off, appearing content to see out the fight and take the points victory.
Cordina sensed his chance was slipping away and began to launch some more committed attacks of his own, only for Tojibaev to reply with a rapid combination to the body - leaving it no surprise when the scores were read out in the Uzbek's favour.
Ireland's lightweight David Oliver Joyce also suffered elimination after losing a unanimous decision to Azerbaijan's Albert Selimov, with three scores of 29-28.
Fellow Irishman Michael O'Reilly has been ruled out of the Olympics after electing not to contest a provisional suspension imposed upon him for a positive drugs test.
The Olympic Council of Ireland announced the 23-year-old, who had been due to begin his campaign in the middleweight division, will not compete.
An OCI statement read: "The OCI can today confirm that Michael O'Reilly is no longer contesting the provisional suspension imposed on him on the 4 August 2016 and will not compete for Team Ireland at the Rio 2016 Olympic Games."
Former IBF champion Amnat Ruenroeng, the last remaining ex-professional in the Games, was stopped in the second round by Sofiane Oumiha in their lightweight bout.